Keywords: عوامل ضد سرطان; Proliferation; Anti-cancer agents; Microalgae; Proteins; Enzymatic extraction;
مقالات ISI عوامل ضد سرطان (ترجمه نشده)
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Keywords: عوامل ضد سرطان; Kinase inhibitor; Polo-like kinase 1; Ras-driven signaling pathways; Non-ATP competitive inhibition; Anti-cancer agents;
Keywords: عوامل ضد سرطان; Heparanase; Heparan sulfate; Inhibitors; Anti-Cancer agents;
Keywords: عوامل ضد سرطان; Small-molecule synthesis; Inhibitors of tubulin polymerization; Vascular disrupting agents; Amino acid prodrug salts; Anti-cancer agents; Combretastatin analogs; Benzosuberene analogs; Dihydronaphthalene analogs
Keywords: عوامل ضد سرطان; Benzoboroxoles; Aminobenzoboroxoles; Anti-Cancer agents; Reductive amination; N-Nitrosoaminobenzoboroxoles; N-BenzoboroxolylureasRTBCSCVOMIFYBJ-UHFFFAOYSA-N; XRUCFATYJVZPLG-UHFFFAOYSA-N; WZNRRHXFHLATES-CXUHLZMHSA-N; SUDGNCMOISRTKY-UHFFFAOYSA-N; KWRPDDSQKZ
Keywords: عوامل ضد سرطان; Virtual screening; Anti-cancer agents; Pharmacophore; Molecular docking
Keywords: عوامل ضد سرطان; Natural products; Phaeosphaeride A; In vitro studies; Anti-cancer agents; A549 cancer cell line; X-ray crystallography;
Keywords: عوامل ضد سرطان; Farnesylthiosalicylic acid; Diamines; Cell apoptosis; Ras-related signaling pathway; Anti-cancer agents;
Keywords: عوامل ضد سرطان; Cancer; Resistance; Anti-cancer agents; Targeted therapies; Hypoxia; Cancer stem cells;
Synthesis, molecular modeling and biological evaluation of potent analogs of 2-methoxyestradiol
Keywords: عوامل ضد سرطان; 2-Methoxyestradiol; Cytostatic activity; Anti-angiogenic effects; Tubulin inhibition; Anti-cancer agents; Friedel-Crafts alkylation;
N-Arylsulfonylsubstituted-1H indole derivatives as small molecule dual inhibitors of signal transducer and activator of transcription 3 (STAT3) and tubulin
Keywords: عوامل ضد سرطان; Signal transducer and activator of transcription (STAT3) inhibitors; Tubulin polymerization inhibitors; Anti-cancer agents; N-arylsulfonylsubstituted-1H indole derivatives;
Synthesis and biological evaluation of pyrimidine derivatives as novel human Pin1 inhibitors
Keywords: عوامل ضد سرطان; Pyrimidine; Pin1; Pin1 inhibitor; PPIase; Anti-cancer agents;
Drug repurposing of novel quinoline acetohydrazide derivatives as potent COX-2 inhibitors and anti-cancer agents
Keywords: عوامل ضد سرطان; Quinoline acetohydrazide; COX 2 inhibitors; Anti-inflammatory agents; Anti-cancer agents; Drug design; Molecular docking study; Lipinski parameter;
An appraisal on synthetic and pharmaceutical perspectives of pyrazolo[4,3-d]pyrimidine scaffold
Keywords: عوامل ضد سرطان; A. flavus; Aspergillus flavus; C. albicans; Candida albicans; cAMP; cyclic adenosine monophosphate; CDK; cyclin-dependent kinase; CNS; central nervous system; COX; cyclooxygenase; CRF; corticotropin-releasing hormone; CRK; cdc2-related kinase; CYC6; cycli
Targeting ubiquitin-proteasome pathway by natural, in particular polyphenols, anticancer agents: Lessons learned from clinical trials
Keywords: عوامل ضد سرطان; Ubiquitin; Proteasome; Anti-cancer agents; Polyphenols; Ubiquitin-proteasome pathway; Oncoproteins; Enzymatic modulator; Cancer;
Benzoboroxoles: Synthesis and applications in medicinal chemistry
Keywords: عوامل ضد سرطان; Boronic acids; Benzoboroxoles; Benzoxaboroles; Anti-fungal agents; Anti-cancer agents; Anti-parasitic agents; Anti-tubercular agents;
Recent advances of RAF (rapidly accelerated fibrosarcoma) inhibitors as anti-cancer agents
Keywords: عوامل ضد سرطان; MAPK; RAF inhibitors; Anti-cancer agents; Abl; Abelson murine leukemia viral oncogene; ATP; Adenine triphosphate; Bcl-2; B-cell lymphoma; CNS; Central nervous system; COX-2; Cyclo-oxygenase enzyme-2; CR; Conserved region; CRD; Cysteine-rich domain; DFG; A
Full length articleChlorambucil labelled with the phenosafranin scaffold as a new chemotherapeutic for imaging and cancer treatment
Keywords: عوامل ضد سرطان; Chlorambucil-phenosafranin; in vitro imaging; Anti-cancer agents;
Synthesis, chemical nuclease activity, and in vitro cytotoxicity of benzimidazole-based Cu(II)/Co(II) complexes
Keywords: عوامل ضد سرطان; Cu(II)/Co(II) complexes; Benzimidazole-based ligand; Chemical nuclease activity; Apoptosis; Anti-cancer agents;
Novel conjugates of endoperoxide and 4-anilinoquinazoline as potential anticancer agents
Keywords: عوامل ضد سرطان; Endoperoxide; 4-Anilinoquinazoline; Conjugates; Anti-cancer agents; EGFR-TKI;
Spirotriazoline oxindoles: A novel chemical scaffold with in vitro anticancer properties
Keywords: عوامل ضد سرطان; Spirooxindole; Triazoline; Cytotoxicity; Anti-cancer agents; Breast cancer;
A comprehensive lipid binding and activity validation of a cancer-specific peptide-peptoid hybrid PPS1
Keywords: عوامل ضد سرطان; Peptoids; Phosphatidylserine; Phosphatidylglycerol; Phosphatidic acid; Liposomes; Anti-cancer agents;
Preparation, characterization and evaluation of novel 1,3,5-triaza-7-phosphaadamantane (PTA)-based palladacycles as anti-cancer agents
Keywords: عوامل ضد سرطان; Palladacycles; Metallacycles; DNA binding studies; Anti-cancer agents; Metallodrugs; 1,3,5-Triaza-7-phosphaadamantane complexes;
An insight on synthetic and medicinal aspects of pyrazolo[1,5-a]pyrimidine scaffold
Keywords: عوامل ضد سرطان; Pyrazolo[1,5-a]pyrimidine; Anti-cancer agents; Anti-infectious agents; CNS agents; Anti-inflammatory agents; Radiopharmaceuticals;
Optimization of pyrazole-containing 1,2,4-triazolo-[3,4-b]thiadiazines, a new class of STAT3 pathway inhibitors
Keywords: عوامل ضد سرطان; STAT3 inhibitor; Triazolo-thiadiazines; Anti-cancer agents; STAT1
Hesperetin and Naringenin sensitize HER2 positive cancer cells to death by serving as HER2 Tyrosine Kinase inhibitors
Keywords: عوامل ضد سرطان; HER2 positive; HER2-TK; HER2-Tyrosine Kinase inhibitors; Naringenin; Hesperetin; Anti-cancer agents; Flavonoids
Synthesis and Pin1 inhibitory activity of thiazole derivatives
Keywords: عوامل ضد سرطان; Thiazole derivatives; Pin1; Pin1 inhibitor; PPIase; Anti-cancer agents;
Synthesis and biological evaluation of novel 2,3-dihydrochromeno[3,4-d]imidazol-4(1H)-one derivatives as potent anticancer cell proliferation and migration agents
Keywords: عوامل ضد سرطان; Chromeno [3,4-d] imidazol-4(1H)-one; Anti-cancer agents; Anti-metastasis
Synthesis and evaluation of second generation Flex-Het scaffolds against the human ovarian cancer A2780 cell line
Keywords: عوامل ضد سرطان; Second generation flexible heteroarotinoids; Flex-Hets; SHetA2 series; Anti-cancer agents; Ovarian cancer;
A novel biological role for nsLTP2 from Oriza sativa: Potential incorporation with anticancer agents, nucleosides and their analogues
Keywords: عوامل ضد سرطان; NsLTP2; Anti-viral drugs; Anti-cancer agents; Drug delivery
Novel pyrrole carboxamide inhibitors of JAK2 as potential treatment of myeloproliferative disorders
Keywords: عوامل ضد سرطان; JAK2; Myeloproliferative disorders; Protein kinase inhibitor; Tumour cell proliferation inhibition; Anti-cancer agents;
One-pot, four-component synthesis of novel cytotoxic agents 1-(5-aryl-1,3,4-oxadiazol-2-yl)-1-(1H-pyrrol-2-yl)methanamines
Keywords: عوامل ضد سرطان; Anti-cancer agents; Cytotoxic activity; 1,3,4-Oxadiazole; Aza-Wittig reaction; Multi-component reactions
Synthesis, in vitro cytotoxicity and apoptosis inducing study of 2-aryl-3-nitro-2H-chromene derivatives as potent anti-breast cancer agents
Keywords: عوامل ضد سرطان; Anti-cancer agents; Apoptosis; Caspase-3; 2H-chromene; β-Nitrostyrene
Pyrrole-3-carboxamides as potent and selective JAK2 inhibitors
Keywords: عوامل ضد سرطان; JAK2; Myeloproliferative disorders; Protein kinase inhibitor; Tumour cell proliferation inhibition; Anti-cancer agents
Fragment-based hit discovery and structure-based optimization of aminotriazoloquinazolines as novel Hsp90 inhibitors
Keywords: عوامل ضد سرطان; Fragment based hit discovery; FAXS-NMR screening; Structure-based design; Hsp90 inhibitors; Anti-cancer agents
Discovery of NMS-E973 as novel, selective and potent inhibitor of heat shock protein 90 (Hsp90)
Keywords: عوامل ضد سرطان; Fragment based drug discovery; Tumor cell proliferation inhibition; Anti-cancer agents;
Discovery and optimization of pyrrolo[1,2-a]pyrazinones leads to novel and selective inhibitors of PIM kinases
Keywords: عوامل ضد سرطان; PIM kinases; Natural product scaffold; Pyrrolopyrazinone; Kinase selectivity; Anti-cancer agents;
2H-chromene derivatives bearing thiazolidine-2,4-dione, rhodanine or hydantoin moieties as potential anticancer agents
Keywords: عوامل ضد سرطان; Anti-cancer agents; Cytotoxicity; 2H-chromene; Thiazolidine-2,4-dione; Rhodanine; Hydantoin
Synthesis, spectroscopic characterization and anti-cancer properties of new gold(III)–alkanediamine complexes against gastric, prostate and ovarian cancer cells; crystal structure of [Au2(pn)2(Cl)2]Cl2·H2O
Keywords: عوامل ضد سرطان; Gold(III) diamine complexes; Anti-cancer agents; MTT assay; Gastric cancer; Prostate cancer; Ovarian cancer; Apoptosis
Bio-inspired synthesis and biological evaluation of a colchicine-related compound library
Keywords: عوامل ضد سرطان; Bio-inspired synthesis; Colchicine-like compounds; Natural products; Oxidative coupling; Anti-cancer agents
Structural modifications modulate stability of glutathione-activated arylated diazeniumdiolate prodrugs
Keywords: عوامل ضد سرطان; Nitric oxide; Diazeniumdiolate prodrugs; JS-K; Glutathione; Anti-cancer agents;
Synthesis and biological evaluation of novel human Pin1 inhibitors with benzophenone skeleton
Keywords: عوامل ضد سرطان; Benzophenone; Pin1; Pin1 inhibitor; PPIase; Anti-cancer agents;
Asymmetrical 2,6-bis(benzylidene)cyclohexanones: Synthesis, cytotoxic activity and QSAR study
Keywords: عوامل ضد سرطان; Anti-Cancer agents; Cytotoxic activity; Curcuminoids; Benzylidene cyclohexanone
Amide-modified prenylcysteine based Icmt inhibitors: Structure-activity relationships, kinetic analysis and cellular characterization
Keywords: عوامل ضد سرطان; Isoprenylcysteine carboxyl methyltransferase; Methylesterification; Icmt; Enzyme inhibition; Ras proteins; Anti-cancer agents; Prenylation; Methyl transferase;
Chemistry of DNA minor groove binding agents
Keywords: عوامل ضد سرطان; DNA minor grooves; Anti-cancer agents; Distamycin; Netropsin; Benzamides; Polypeptides
Probing the isoprenylcysteine carboxyl methyltransferase (Icmt) binding pocket: Sulfonamide modified farnesyl cysteine (SMFC) analogs as Icmt inhibitors
Keywords: عوامل ضد سرطان; Inhibitor; Methyltransferase; Enzymes; Isoprenoid; Signal transduction; Anti-cancer agents
Chromomycin SA analogs from a marine-derived Streptomyces sp.
Keywords: عوامل ضد سرطان; Natural products; Isolation; Marine actinomycetes; Anti-cancer agents; Aureolic acid; Chromomycin;
Mitochondrial targeting of α-tocopheryl succinate enhances its pro-apoptotic efficacy: A new paradigm for effective cancer therapy
Keywords: عوامل ضد سرطان; BH3; Bcl-2 homology domain 3; CII; complex II; ChIP; chromatin immunoprecipitation; DHE; dihydroethidium; DMPO; 5,5-dimethyl-1-pyrroline N-oxide; EPR; electron paramagnetic resonance; MIM; mitochondrial inner membrane; MitoQ; mitochondrially targeted coen
Synthesis and biological evaluation of novel quinazoline-derived human Pin1 inhibitors
Keywords: عوامل ضد سرطان; Quinazoline; Pin1; Pin1 inhibitor; PPIase; Anti-cancer agents
Insect natural products and processes: New treatments for human disease
Keywords: عوامل ضد سرطان; Insect natural products; Medicinal drugs; Folk medicine; Honey; Venom; Silk; Cantharidin; Maggots; Antimicrobial factors; Anticoagulants; Anti-cancer agents