New phosphorus dendrimers with chiral ferrocenyl phosphine-thioether ligands on the periphery for asymmetric catalysis

Chiral ferrocenyl phosphine-thioether ligands have been covalently bound on the periphery of 4 phosphorus dendrimers (generations 1–4) having a cyclotriphosphazene core and on one model compound. These new dendrimers proved to be efficient ligands for the palladium-catalyzed asymmetric allylic substitution reaction (ee up to 93%).

The synthesis of new dendrimers with chiral ferrocenyl phosphine-thioether ligands on the periphery (up to the fourth generation) and their use in asymmetric allylic substitution is reported.Figure optionsDownload as PowerPoint slide