کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1323497 | 1499935 | 2012 | 7 صفحه PDF | دانلود رایگان |
Quinones have various pharmacological properties including antibacterial, antifungal, antiviral, anti-inflammatory, antipyretic and anticancer activity. Two novel 2,3-disubstituted 1,4-naphthoquinones and their metal complexes were synthesised, characterized and tested. The cytotoxic potential of the novel 2,3-disubstituted 1,4-naphthoquinones and their metal complexes was studied against L929 murine fibroblasts cells grown in vitro. The treatment resulted in a concentration-dependent cytotoxicity as indicated by MTT assay.
A novel organic compound from the 2,3-disubstituted naphthoquinone class is presented.Figure optionsDownload as PowerPoint slideHighlights
► Quinones are reported to exhibit pharmacological properties.
► Novel 2,3-disubstituted 1,4-naphthoquinones and their complexes were synthesized.
► Cytotoxic potential of the novel 2,3-disubstituted 1,4-naphthoquinones.
► Physical-chemical determinations suggest that Pt and Ni complexes are [ML2] type.
Journal: Journal of Organometallic Chemistry - Volume 700, 1 March 2012, Pages 13–19