A straight forward in situ preparation of NHC-substituted phosphapalladacycles

A new simple technique for the preparation of NHC-substituted phosphapalladacycles is reported by using phosphapalladacycle acetate precursors and azolium tetrafluoroborate salts in DMSO. The one-pot synthesis avoids multi-step reactions employing free carbenes. With this technique, NHC-substituted phosphapalladacycles were thus obtained that are not accessible via the free carbene route.

The preparation of NHC-substituted phosphapalladacycles via an in situ method by using phosphapalladacycle acetate precursors and azolium tetrafluoroborate salts in DMSO was accomplished. With this method it is possible to prepare NHC-palladacycles with a broader variation of NHC’s.Figure optionsDownload as PowerPoint slide