کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1324297 1499889 2014 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Au(I)–N-heterocyclic carbene complex-catalyzed synthesis of 1-substituted benzo[b][1,4]diazepines from N-substituted o-phenylenediamines and terminal alkynes
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی معدنی
پیش نمایش صفحه اول مقاله
Au(I)–N-heterocyclic carbene complex-catalyzed synthesis of 1-substituted benzo[b][1,4]diazepines from N-substituted o-phenylenediamines and terminal alkynes
چکیده انگلیسی


• An Au(I)-NHC-catalyzed process for benzo[b][1,4]diazepines was developed.
• 1-Substituted benzo[b][1,4]diazepines were efficiently prepared.
• Fused tricyclic benzo[b][1,4]diazepines were accessed for the first time.

1-Substituted benzo[b][1,4]diazepines which are difficult to synthesize by traditional methods have been prepared by an Au(I)–N-heterocyclic carbene complex-catalyzed tandem hydroamination/cyclization process. This protocol features the one-pot formation of a seven-membered N-heterocycle via atom-economic hydroamination/cyclization reactions of readily available N-substituted o-phenylenediamines and terminal alkynes. Based on this strategy, fused tricyclic benzo[b][1,4]diazepines have been accessed for the first time.

1-Substituted and fused polycyclic benzo[b][1,4]diazepines which are difficult to be accessed previously have been synthesized by Au(I)–NHC complex-catalyzed tandem hydroamination/cyclization protocol.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Organometallic Chemistry - Volume 751, 1 February 2014, Pages 438–442
نویسندگان
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