کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1324860 | 977358 | 2011 | 8 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Asymmetric hydroamination/cyclization catalyzed by group 4 metal complexes with chiral biaryl-based ligands Asymmetric hydroamination/cyclization catalyzed by group 4 metal complexes with chiral biaryl-based ligands](/preview/png/1324860.png)
Group 4 metal complexes based on chiral biaryl ligands are readily prepared by a convenient amine elimination procedure, and they are efficient catalysts for the asymmetric hydroamination/cyclization of aminoalkenes. The biaryl-based ligands are highly modular enabling facile tuning of the catalyst reactivity and selectivity. The corresponding heterocyclic products have been obtained in excellent enantiomeric excesses (up to 93%) using sterically hindered C2-symmetric titanium and zirconium mesitoylamidate complexes such as [1,1′-(C10H10)2-2,2′-{NCO(2,4,6-Me3C6H2)}2]M(NMe2)2 (M = Ti, Zr). These results are presented in this short review.
This short review summarizes recent work on the asymmetric hydroamination/cyclization catalyzed by group 4 metal complexes with chiral biaryl-based ligands.Figure optionsDownload as PowerPoint slide
Journal: Journal of Organometallic Chemistry - Volume 696, Issue 1, 1 January 2011, Pages 68–75