Stereospecific palladium-catalyzed borylation reaction of 1-alkenyl halides with diispropylaminoborane

The palladium-catalyzed borylation reaction of 1-alkenyl halides with diisopropylaminoborane leads efficiently and stereospecifically to the corresponding trans-1-alkenyl(diisopropylamino)boranes in good yields.

Bsp2–HBsp2–H containing (E)-1-alkenyl boron derivatives as stable and isolable species are accessible stereospecifically in medium to high yields from 1-alkenyl halides via a palladium-catalyzed borylation reaction involving diisopropylaminoborane as an efficient BH transferring agent.Figure optionsDownload as PowerPoint slide