کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1328450 977574 2006 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Imine hydrogenation catalyzed by iridium complexes comprising monodentate chiral phosphoramidites and N-donor ligands
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی معدنی
پیش نمایش صفحه اول مقاله
Imine hydrogenation catalyzed by iridium complexes comprising monodentate chiral phosphoramidites and N-donor ligands
چکیده انگلیسی

The relatively inexpensive chiral monodentate phosphoramidite (S)-MONOPHOS may be used in combination with pyridines to prepare iridium complexes effective for catalysis of asymmetric imine hydrogenation with comparable enantioselectivity to some of those containing more costly chiral bidentate phosphines. [Ir(cod)((S)-MONOPHOS)(L)]BArF (cod = 1,5-cyclooctadiene; L = 3-methylisoquinoline, acridine, 2,6-lutidine, acetonitrile, or 2,3,3-trimethylindolenine; BArF = tetrakis[3,5-bis(trifluoromethyl)phenyl]borate) are efficient catalysts for the asymmetric hydrogenation of 2,3,3-trimethylindolenine. An important observation is that the catalyst containing acridine is more enantioselective than the catalyst derived from 2,3,3-trimethylindolenine which suggests that the other N-donor ligands are not readily displaced by the substrate during the catalytic cycle.

The relatively inexpensive chiral monodentate phosphoramidite (S)-MONOPHOS may be used in combination with pyridines to prepare iridium complexes effective for catalysis of asymmetric imine hydrogenation with comparable enantioselectivity to some catalysts containing more costly chiral bidentate phosphines.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Organometallic Chemistry - Volume 691, Issue 23, 15 November 2006, Pages 4945–4955
نویسندگان
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