کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1355532 981026 2015 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Imidazopyridines as a source of biological activity and their pharmacological potentials—Infrared and Raman spectroscopic evidence of their content in pharmaceuticals and plant materials
ترجمه فارسی عنوان
ایمیدازوپیریدینها به عنوان منبع فعالیت بیولوژیکی و پتانسیل دارویی آنها. شواهد اسپکتروسکوپی مادون قرمز و رامان در محتوای آنها در مواد دارویی و مواد گیاهی
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
چکیده انگلیسی

Derivatives of imidazopyridine are used in medicinal chemistry due to their biological and pharmaceutical properties. This review article presents imidazopyridine pharmacological activity as antiinflammatory, anticancer, antiviral, antiosteoporotic, antiparasitic, and antihypertensive agents by studying its various synthesized derivatives. Some of compounds with imidazopyridine skeleton are used in psychiatry and autoimmune disorders. The presented data suggest that IR and Raman spectra measurements are a good methods for identification and characterization of the compounds containing imidazopyridine core. Two stretching vibrations: νas(Φ) and νs(Φ) are of a diagnostic importance. The appearance of these bands in the IR and Raman spectra of some plants, tissues and pharmaceuticals confirms the presence of imidazopyridine skeleton in these substances.

Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry - Volume 23, Issue 18, 15 September 2015, Pages 6087–6099
نویسندگان
,