کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1355951 | 981077 | 2010 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Synthesis of stilbene-fused 2′-hydroxychalcones and flavanones
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
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چکیده انگلیسی
Synthesis of stilbene-fused chalcones and flavanones were successfully completed. Molecules were designed in a way to mimic the structural features of both “stilbene and chalcones” or “stilbene and flavanones” at the same time, and synthesized by three steps. Heck reactions of 3-bromobenzaldehyde with styrene derivatives gave corresponding (E)-stilbenes, which were reacted with acetophenones to furnish stilbene-fused 2′-hydroxychalcones under basic conditions. Finally, intramolecular cyclization reactions were performed to produce stilbene-fused flavanones.
Synthesis of two small matrixes (4 × 4) of stilbene-fused chalcones and stilbene-fused flavanones were successfully completed.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic Chemistry - Volume 38, Issue 4, August 2010, Pages 139–143
Journal: Bioorganic Chemistry - Volume 38, Issue 4, August 2010, Pages 139–143
نویسندگان
İsmail Akçok, Ali Çağır,