کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1355951 981077 2010 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis of stilbene-fused 2′-hydroxychalcones and flavanones
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Synthesis of stilbene-fused 2′-hydroxychalcones and flavanones
چکیده انگلیسی

Synthesis of stilbene-fused chalcones and flavanones were successfully completed. Molecules were designed in a way to mimic the structural features of both “stilbene and chalcones” or “stilbene and flavanones” at the same time, and synthesized by three steps. Heck reactions of 3-bromobenzaldehyde with styrene derivatives gave corresponding (E)-stilbenes, which were reacted with acetophenones to furnish stilbene-fused 2′-hydroxychalcones under basic conditions. Finally, intramolecular cyclization reactions were performed to produce stilbene-fused flavanones.

Synthesis of two small matrixes (4 × 4) of stilbene-fused chalcones and stilbene-fused flavanones were successfully completed.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic Chemistry - Volume 38, Issue 4, August 2010, Pages 139–143
نویسندگان
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