کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1356379 | 1500472 | 2012 | 7 صفحه PDF | دانلود رایگان |
Starting from 4-amino-antipyrine, six new compounds were synthesized and characterized. The new compounds contain moieties with particular properties, such are ionophore (benzo-15-crown-5), fluorescent (nitrobenzofurazan), stable free radical (nitroxide), or other types of biological active residues, like nitroderivatives, antipyrine or isoniazid residues. They were fully characterized by appropriate means (1H and 13C NMR, IR, UV–Vis, fluorescence, EPR, elemental analysis) and some of their biological properties were evaluated. Hydrophobicity (RM0, log P), total antioxidant capacity (TAC), and antimicrobial properties are also presented and discussed.
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► New antypirine derivatives synthesized and characterized.
► Contain moieties with particular properties.
► Biological activity evaluated.
Journal: Bioorganic Chemistry - Volumes 41–42, April–June 2012, Pages 6–12