کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1356757 | 981151 | 2008 | 5 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Cinnamoyl- and hydroxycinnamoyl amides of glaucine and their antioxidative and antiviral activities Cinnamoyl- and hydroxycinnamoyl amides of glaucine and their antioxidative and antiviral activities](/preview/png/1356757.png)
The aporphine alkaloid glaucine has been converted into 3-aminomethylglaucine and its free amino group has been linked to cinnamic, ferulic, sinapic, o-, and p-coumaric acids. The antioxidative potential of the synthesized amides was studied against DPPH∗ test. All of the tested compounds demonstrated higher radical scavenging activity than glaucine and 3-aminomethylglaucine, and lower antioxidative effect than the free hydroxycinnamic acids. The newly synthesized compounds were tested in vitro for antiviral activity against viruses belonging to different taxonomic groups.
Cinnamoyl-, feruloyl-, sinapoyl-, o-, and p-coumaroyl amides of 3-aminomethylglaucine were synthesized, and their antiviral activity and antioxidant potential against DPPH∗ test were estimated.Figure optionsDownload as PowerPoint slide
Journal: Bioorganic & Medicinal Chemistry - Volume 16, Issue 15, 1 August 2008, Pages 7457–7461