Carbonic anhydrase inhibitors; Fluorinated phenyl sulfamates show strong inhibitory activity and selectivity for the inhibition of the tumor-associated isozymes IX and XII over the cytosolic ones I and II

Ki(CA I) = 53-415 nM; Ki(CA II) = 20-113 nM; Ki(CA IX) = 2.8-47 nM; Ki(CA XII)) 1.9-35 nM.