کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1366206 981585 2007 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Dual bioactivity of resveratrol fatty alcohols: Differentiation of neural stem cells and modulation of neuroinflammation
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Dual bioactivity of resveratrol fatty alcohols: Differentiation of neural stem cells and modulation of neuroinflammation
چکیده انگلیسی

The synthesis of resveratrol fatty alcohols (RFAs), a new class of small molecules presenting strong potential for the treatment of neurological diseases, is described. RFAs, hybrid compounds combining the resveratrol nucleus and ω-alkanol side chains, are able to modulate neuroinflammation and to induce differentiation of neural stem cells into mature neurons. Acting on neuroprotection and neuroregeneration, RFAs represent an innovative approach for the treatment or cure of neuropathies.

Synthesis of resveratrol fatty alcohols (RFAs), a new class of molecules acting simultaneously on neuroprotection and neuroregeneration is described. RFAs represent an innovative approach for the treatment of different neuropathies.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 17, Issue 15, 1 August 2007, Pages 4218–4222
نویسندگان
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