کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1366611 981597 2005 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A novel method of estimation of lipophilicity using distance-based topological indices: dominating role of equalized electronegativity
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
A novel method of estimation of lipophilicity using distance-based topological indices: dominating role of equalized electronegativity
چکیده انگلیسی

Attempt is made to propose yet another method of estimating lipophilicity of a heterogeneous set of 223 compounds. The method is based on the use of equalized electronegativity along with topological indices. It was observed that excellent results are obtained in multiparametric regression upon introduction of indicator parameters. The results are discussed critically on the basis various statistical parameters.

Attempt is made to propose yet another method for the estimation of lipophilicity of a heterogeneous set of 223 compounds. The method is based on the use of topological indices along with equalized electronegativity. The results have shown that excellent results are obtained in multiparametric regression upon introduction of indicator parameters.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry - Volume 13, Issue 6, 15 March 2005, Pages 2109–2120
نویسندگان
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