کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1367614 | 981641 | 2006 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Design and synthesis of cyclic and linear peptide-agarose tools for baiting interacting protein partners of GPCRs
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Design and synthesis of cyclic and linear peptide-agarose tools for baiting interacting protein partners of GPCRs Design and synthesis of cyclic and linear peptide-agarose tools for baiting interacting protein partners of GPCRs](/preview/png/1367614.png)
چکیده انگلیسی
A ligation strategy for the synthesis of cyclic and linear peptides covalently linked to agarose beads designed as baits to identify new interacting partners of intracellular loops of the V2 vasopressin receptor, a member of the G-protein-coupled receptor family, is reported. The peptide-resin conjugates were subsequently shown to interact specifically with a fraction of proteins present in cellular lysates.
The synthesis of affinity supports designed to identify GPCR partners is reported.Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 16, Issue 3, 1 February 2006, Pages 521–524
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 16, Issue 3, 1 February 2006, Pages 521–524
نویسندگان
Sébastien Granier, Frédéric Jean-Alphonse, Hélène Déméné, Gilles Guillon, Robert Pascal, Christiane Mendre,