Discovery of a novel and potent series of dianilinopyrimidineurea and urea isostere inhibitors of VEGFR2 tyrosine kinase

A series of dianilinopyrimidineureas demonstrate potency as VEGFR2 kinase inhibitors.

A series of dianilinopyrimidineureas show potency as VEGFR2 kinase inhibitors.Figure optionsDownload as PowerPoint slide