کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1371895 981857 2009 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Enlarged analogues of uniconazole, new azole containing inhibitors of ABA 8′-hydroxylase CYP707A
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Enlarged analogues of uniconazole, new azole containing inhibitors of ABA 8′-hydroxylase CYP707A
چکیده انگلیسی

We enlarged the uniconazole (UNI) molecule to find a specific inhibitor of abscisic acid (ABA) 8′-hydroxylase, and synthesized various UNI derivatives that were substituted with hydrophilic and hydrophobic groups at the 4-chlorine of the phenyl group of UNI using click chemistry. Considering its potency in ABA 8′-hydroxylase inhibition, its small effect on seedling growth, and its ease of application, UT4, the UNI derivative containing the C4 alkyltriazole, was the best candidate for a highly selective inhibitor of ABA 8′-hydroxylase.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 19, Issue 19, 1 October 2009, Pages 5782–5786
نویسندگان
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