کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1378163 | 981995 | 2010 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Protective effect of Potentillaanserine polysaccharide (PAP) on hydrogen peroxide induced apoptosis in murine splenic lymphocytes
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موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The study was carried out to investigate protective effect of Potentilla anserine polysaccharide on the process of apoptosis induced by hydrogen peroxide (H2O2) in murine splenic lymphocytes in vitro. The results showed that apoptosis occured in murine splenic lymphocytes treated with H2O2in vitro at a concentration of 200 μmol/L. Treatments with Potentilla anserine polysaccharide at concentrations of 50, 100, 200 or 400 μg/mL decreased the amount of apoptosis cells and the anti-apoptosis effect showed a dose dependent manner increase. The results showed that PAP reduced intracellular oxidative damages and dose-dependently inhibited apoptosis. This suggests that PAP is a potential anti-apoptotic agent.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Polymers - Volume 79, Issue 2, 20 January 2010, Pages 356–361
Journal: Carbohydrate Polymers - Volume 79, Issue 2, 20 January 2010, Pages 356–361
نویسندگان
TingJun Hu, Xiaojie Wei, Xia Zhang, FuSheng Cheng, XueHong Shuai, Ling Zhang, Le Kang,