Determining the solution conformational entropy of oligosaccharides by SEC with on-line viscometry detection

- Solution conformational entropy of oligosaccharides determined by SEC/viscometry.
- SEC/viscometry compares well to benchmark chromatography method for determining ΔS.
- Comparison is made among several series of (1 → 4)-β-d-linked oligosaccharides, DP 2-6.
- Sensitivity of viscometry in the oligomeric region of carbohydrates is addressed.