Seven new vernocuminosides from the stem bark of Vernonia cumingiana Benth

Seven new stigmastane-type steroidal glycosides, vernocuminosides H–N, have been isolated from the stem bark of Vernonia cumingiana Benth. The structures of these compounds were determined by NMR spectrometric methods including HSQC, HMBC, 1H–1H COSY, and NOE, as well as circular dichroism experiments. Anti-inflammatory activities of vernocuminosides I and K–N were determined.

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