Glycosylation in room temperature ionic liquid using unprotected and unactivated donors

Glycosylation in room temperature ionic liquid is demonstrated using unprotected and unactivated donors. Modest yields of simple benzyl glycosides and disaccharides of glucose, mannose and N-acetylgalactosamine were obtained in 1-ethyl-3-methylimidazolium benzoate with Amberlite IR-120 (H+) resin or p-toluenesulfonic acid as promoters.

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