کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1387809 1500896 2012 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis of imidazo[2,1-b]thiazoles linked to an unprotected carbohydrate moiety
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Synthesis of imidazo[2,1-b]thiazoles linked to an unprotected carbohydrate moiety
چکیده انگلیسی

Two series of imidazo[2,1-b]thiazoles substituted on C-3 or C-5 with an unprotected carbohydrate moiety were synthesized. Different protective groups for position 3 of the carbohydrate moiety were tested (acetyl, tert-butyldimethylsilyl (TBDMS), and p-methoxybenzyl (PMB)) and the latter turn out to be the best strategy to obtain the desired products. Full deprotection of the carbohydrate was performed successfully in only one step.

Figure optionsDownload as PowerPoint slideHighlights
► Synthesis of imidazo[2,1-b]thiazoles linked to an unprotected carbohydrate moiety.
► A convenient protective group for position 3 of a carbohydrate.
► Microwave assistance of N-alkylation step.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Research - Volume 355, 1 July 2012, Pages 79–86
نویسندگان
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