An efficient method for the selective synthesis of 2-deoxy-2-iodo-glycosides by O-glycosidation of d-glucal using I2–Cu(OAc)2

An efficient and convenient method for the synthesis of 2-deoxy-2-iodo-O-glycosides from tri-O-acetyl-d-glucal with various alcohols by using I2–Cu(OAc)2 is described. The 21 examples of corresponding glycosides were obtained in high yields, with good anomeric selectivity.

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