کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1388162 | 1500830 | 2016 | 8 صفحه PDF | دانلود رایگان |
• A convergent template assisted synthesis of sugar-based chiral macrocycles has been described.
• The host–guest inclusion studies have revealed selective interactions of the synthesized macrocycle with the primary instead of secondary ammonium salt.
• The synthesized chiral macrocycle also discriminates between D- and L-phenylalanine methyl ester salts as revealed by 1H NMR spectral studies of the host-guest mixture.
A convergent template assisted synthesis of sugar-based chiral macrocycles has been achieved. The host–guest inclusion studies have revealed significant interactions of the synthesized macrocycle with primary over secondary ammonium salt. The chiral macrocyle also discriminates between D- and L-phenylalanine methyl ester hydrochlorides as revealed by 1H NMR spectral studies on the mixture of the host and the guest molecules.
A highly convergent template assisted synthesis of chiral macrocycles, which are cyclic homodimer of azido-alkyne furanose sugar derivatives, has been successfully achieved and evaluated for host-guest inclusion complex formation ability using benzyl- and dibenzyl ammonium perchlorate salt as guests. One of the chiral macrocycles showed recognition for D- and L-phenylalanine methyl ester hydrochloride salts.Figure optionsDownload as PowerPoint slide
Journal: Carbohydrate Research - Volume 421, 8 February 2016, Pages 25–32