کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1388911 982829 2007 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Novel chalcogenides of thymidine and uridine: synthesis, properties and applications
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Novel chalcogenides of thymidine and uridine: synthesis, properties and applications
چکیده انگلیسی

A facile and efficient methodology has been developed for the synthesis of dithymidine and di-uridine derived disulfides using benzyltriethylammonium tetrathiomolybdate as a sulfur transfer reagent. However, a similar reaction of thymidine derivative with tetraethylammonium tetraselenotungstate as a selenium transfer reagent resulted in the formation of an unexpected cyclic diselenide. The disulfide derivatives of nucleosides have been used as precursors in a tandem disulfide cleavage-Michael addition/ring opening reactions to construct aminoacid and carbocyclic derivatives of nucleosides.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Research - Volume 342, Issue 9, 2 July 2007, Pages 1151–1158
نویسندگان
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