کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1390188 | 1500857 | 2014 | 6 صفحه PDF | دانلود رایگان |
![عکس صفحه اول مقاله: Chemical synthesis of a tetrasaccharide related to the exocellular polysaccharide from Rhodococcus sp. RHA1 Chemical synthesis of a tetrasaccharide related to the exocellular polysaccharide from Rhodococcus sp. RHA1](/preview/png/1390188.png)
• Synthesis of the repeating unit of the EPS from Rhodococcus sp. RHA1.
• Activation of thioglycoside using NIS and La(OTf)3.
• Late stage TEMPO mediated oxidation.
Chemical synthesis of the tetrasaccharide related to the exocellular polysaccharide from Rhodococcus sp. RHA1 is reported. The stereoselective glycosylations were achieved by activation of the thioglycoside donors using N-iodosuccinimide in the presence of La(OTf)3 varying temperature per the need of 1,2-cis or 1,2-trans glycosylations. The target tetrasaccharide is reported in the form of its p-methoxyphenyl glycoside that can be cleaved selectively from the per-O-acetylated derivative allowing further glycoconjugate formation using trichloroacetimidate chemistry.
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Journal: Carbohydrate Research - Volume 394, 23 July 2014, Pages 26–31