کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1390332 | 1500883 | 2013 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Concise synthesis of α-galactosyl ceramide from d-galactosyl iodide and d-lyxose
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی آلی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Concise synthesis of α-galactosyl ceramide from d-galactosyl iodide and d-lyxose Concise synthesis of α-galactosyl ceramide from d-galactosyl iodide and d-lyxose](/preview/png/1390332.png)
چکیده انگلیسی
α-Galactosyl ceramide is synthesized from d-lyxose in 32% overall yield in five steps. The short and efficient protocol involves a one-pot protection and glycosidation of d-lyxose with d-galactosyl iodide as a key step. The α-linked disaccharide obtained was subsequently transformed into α-galactosyl ceramide in four steps involving Z-selective Wittig olefination at C-1, stereo-inversion at C-4 using azide, one-pot reduction of azide and amidation, and global deprotection.
Figure optionsDownload as PowerPoint slide
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Research - Volume 368, 7 March 2013, Pages 35–39
Journal: Carbohydrate Research - Volume 368, 7 March 2013, Pages 35–39
نویسندگان
Yu-Fen Yen, Suvarn S. Kulkarni, Chun-Wei Chang, Shun-Yuan Luo,