کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1390758 983137 2008 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis of β-C-glycopyranosyl-1,4-naphthoquinone derivatives and their cytotoxic activity
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Synthesis of β-C-glycopyranosyl-1,4-naphthoquinone derivatives and their cytotoxic activity
چکیده انگلیسی

β-C-Glucosyl and β-C-galactosyl-1,4-dimethoxynaphthalenes have been synthesized using a F3CCO2Ag/SnCl4 promoted Friedel–Crafts electrophilic substitution reaction. Both glycosyl acetates and methyl glycosides can be used as glycosyl donors. Further oxidation afforded the corresponding β-C-glycosyl-1,4-naphthoquinones. The in vitro cytotoxic activity of these compounds was evaluated against the A375 cell line.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Research - Volume 343, Issue 4, 17 March 2008, Pages 773–779
نویسندگان
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