کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1390971 983172 2006 17 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
De novo asymmetric syntheses of C-4-substituted sugars via an iterative dihydroxylation strategy
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
De novo asymmetric syntheses of C-4-substituted sugars via an iterative dihydroxylation strategy
چکیده انگلیسی

A short and highly efficient route to various C-4 substituted sugar lactones has been developed. The key to the overall transformation is the sequential osmium-catalyzed dihydroxylation reaction of substituted 2,4-dienoates and an allylic substitution at the C-4 position. When the Sharpless AD-mix procedure is used in a matched sense for the second dihydroxylation reaction, it results in an exceedingly diastereo- and enantioselective synthesis of several C-4-substituted sugars.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Research - Volume 341, Issue 10, 24 July 2006, Pages 1505–1521
نویسندگان
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