کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1390978 983172 2006 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Synthesis of the Glc3Man N-glycan tetrasaccharide by iterative allyl IAD
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Synthesis of the Glc3Man N-glycan tetrasaccharide by iterative allyl IAD
چکیده انگلیسی

The synthesis of the tetrasaccharide α-d-Glcp-(1→2)-α-d-Glcp-(1→3)-α-d-Glcp-(1→3)-α-d-Manp-OMe, corresponding to the terminal tetrasaccharide portion of the glucose terminated arm of the N-glycan tetradecasaccharide, was achieved with complete stereocontrol by the use of iterative allyl protecting group mediated intramolecular aglycon delivery (allyl IAD) demonstrating the utility of intramolecular glycosylation for the stereocontrolled construction of multiple glycosidic linkages during the synthesis of an oligosaccharide.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Carbohydrate Research - Volume 341, Issue 10, 24 July 2006, Pages 1609–1618
نویسندگان
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