Fluorescence-detectable, star-shaped polylactic acid construction for implantation

To reduce the complexity to monitor the bio-absorbable polymer in the implants, a new hyper branched star shaped polymer was developed with the synergetic combination of bio-absorbability and fluorescent characteristics. These hyper branched polymers were synthesized using arm fist method (AFM). This kind of advanced fluorescent specific bioabsorbable polymer (FBAP’s) is in high demand due to several advantages in replacing traditional materials for implants. Here, we have reported the molecular arrangement of the hyper branched polymer with respect to the fluorescent behavior.

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► Star shaped PLA (SSPLA) prepared by the arm fist method.
► Separated two, three, four arms individually by column chromatography.
► SSPLA was detectable using in vivo fluorescent imaging.
► SSPLA having synergetic properties of fluorescent emission with long stokes shifts biocompatibility.
► Potential biomedical applications.