کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
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1400327 | 984550 | 2005 | 10 صفحه PDF | دانلود رایگان |
Biodegradable polyurethane elastomers with potential for applications in medical implants with tunable degradation rate and physical properties were synthesized from reaction of epoxy terminated polyurethanes (EUP) with 1,6-hexamethylene diamine (HMDA) as curing agent. Poly(ε-caprolactone) (PCL) and poly(ethylene glycol) (PEG) as well as 1,6-hexamethylene diisocyanate (HDI) were used for preparation of isocyanate terminated polyurethanes which were subsequently blocked with glycidol to prepare EUPs. All materials were characterized by conventional methods, and their properties were studied fully. Results showed that elastomers based on PEG exhibit superior degradation rate and inferior mechanical properties in comparison to elastomers based on PCL. Optimum degradation rate and mechanical properties were obtained from elastomers made from mixture of PCL and PEG base EUPs.
Journal: European Polymer Journal - Volume 41, Issue 10, October 2005, Pages 2370–2379