Two new flavonoids from Artemisa sacrorum Ledeb and their antifungal activity

• Two new flavonoids were isolated from A. sacrorum.
• This is the first report on the structure elucidation of two new compounds based on spectroscopic methods.
• The flavonoids exhibited appreciable inhibition of mycelial growth, with variable activities depending on Fod race.

Two new flavonoids, named as sacriflavone A (1) and sacriflavone B (2), were isolated from the CHCl3 extract of Artemisa sacrorum Ledeb (A. sacrorum). The structures of the isolated compounds have been elucidated unambiguously by UV, MS, and a series of 1D and 2D NMR analyses. The isolated compounds exhibited antifungal activity against different Fusarium oxysporum f. sp. dianthi pathotypes.

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