کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1402342 1501743 2014 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Design, synthesis, linear and nonlinear photophysical properties and biological imaging application of a novel Λ-type pyrimidine-based thiophene derivative
ترجمه فارسی عنوان
طراحی، ترکیب، خواص فتوفیزیکی خطی و غیر خطی و کاربرد تصویربرداری بیولوژیکی مشتق شده از تیوفین مبتنی بر پیریمیدین جدید
کلمات کلیدی
مشتق شده از تیوفن پیریمیدین، ساختار کریستالی، جذب دو فوتون، تصویربرداری بیولوژیکی
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
چکیده انگلیسی


• A novel D–π–A–π–D type thiophene pyrimidine derivative (L) was obtained.
• L belongs to P212121 non-centrosymmetric space group.
• L shows strong third-order nonlinear optical response.
• L is capable of detecting the cytoplasm section in HepG2 cells.

A novel D–π–A–π–D type thiophene pyrimidine derivative, 2,2′-thiophene-4, 6-bis (4-N,N-diethylbenzene ethenyl) pyrimidine (L), was designed, synthesized via Knoevenagel and Suzuki coupling reactions, and fully characterized. The results of X-ray diffraction analysis revealed that single crystal of L belongs to P212121 non-centrosymmetric space group, and the whole molecular skeleton exhibits a good coplanarity. Systematic photophysical properties were investigated for L. The connections between the properties and structure were explained relying on theoretical calculation. The thiophene pyrimidine derivative shows strong third-order nonlinear optical response and large two-photon absorption (2PA) cross section in high polar solvents. Finally, preliminary exploration in biological imaging also has been carried out, it shows a good biological application prospect.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Molecular Structure - Volume 1074, 25 September 2014, Pages 33–42
نویسندگان
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