کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1402684 984777 2009 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Molecular recognition capability and rheological behavior in solution of novel lactone-based glycopolymers
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
Molecular recognition capability and rheological behavior in solution of novel lactone-based glycopolymers
چکیده انگلیسی

Novel glycopolymers have been prepared from ethylene–vinyl alcohol copolymers, EVOH. For that purpose, three distinct aminosaccharides (N-(4-aminobutyl)-d-gluconamide (NABG), N-(4-aminobutyl)-O-β-d-galactopyranosyl-(1 → 4)-d-gluconamide (NABL) and N-(4-aminobutyl)-O-β-d-glucopyranosyl-(1 → 4)-d-gluconamide (NABM) have been synthesized. The previous functionalization of these EVOH copolymers is mandatory to activate their hydroxyl reactivity before the subsequent coupling reaction with the aminosaccharides. The activation with carboxylic acid groups by reaction with phthalic anhydride has been chosen in the current investigation because of its almost quantitative yield and the subsequent high modification extent reached (>60%). The glycopolymers that turned out water-soluble (i.e., those based on NABL and NABM) have shown a reversible network formation unusually described in glycopolymers. In addition, their capability to interact with lectins, particularly Concanavalin A and Ricinus communis Agglutinin, has confirmed the specificity of lectin recognition in these glycopolymers.

Novel glycopolymers based on ethylene–vinyl alcohol copolymers and lactones have been developed. Their solutions in water lead to the formation of reversible thermallyinduced networks as well as exhibit molecular recognition to specific lectins.Figure optionsDownload as PowerPoint slide

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Polymer Journal - Volume 45, Issue 11, November 2009, Pages 3176–3186
نویسندگان
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