کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1404790 | 1501698 | 2016 | 7 صفحه PDF | دانلود رایگان |
• Halogen atom based co-crystals for determination of absolute configuration for chiral molecules were synthesized.
• Three cholestanol co-crystals and one l-ascorbic acid co–crystal were obtained.
• Changing the halogen atoms affects the co–crystal formation and the ability to determine absolute configuration.
Heavy atom (chloride, bromide, and iodide) based co-crystals for determination of absolute configuration (AC) for chiral molecules were synthesized and evaluated. Co-crystals of cholestanol and l-ascorbic acid were analysed and the effects and potential benefits of varying the heavy atom are discussed. Changing the halogen atoms (chloride, bromide, or iodide) affects the co–crystal formation, X-ray absorption, and anomalous dispersion, and hence the ability to determine AC.
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Journal: Journal of Molecular Structure - Volume 1119, 5 September 2016, Pages 269–275