کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1407572 1501690 2017 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Molecular structure activity on pharmaceutical applications of Phenacetin using spectroscopic investigation
ترجمه فارسی عنوان
فعالیت ساختاری مولکولی در کاربرد داروهای فنآستین با استفاده از مطالعه اسپکتروسکوپی
کلمات کلیدی
پناهتین، تغییر بوته کروم، اهداکننده غیرنظامی، ضد التهابی انرژی آزاد گیبس،
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
چکیده انگلیسی
The formation of molecular orbitals generally alternate the atomic charge levels due to the asymmetric electron delocalization among the bonds in the compound. The asymmetric charge orientation induced interactive (directed bonds) and repulsive bonds (weak bonds) in the compound. The positive and negative attitude atoms making strong and weak bonds in various places of the molecule and thus direct the overlapping molecular orbitals in different bonds which modify the chemical property of the compound. The electron accretion zone was appeared in the top moiety of the ring while proton accretion part was observed in bottom moiety. The strong bond is found at C13O14 in the left ligand group which was significant to stress the major role in the new chemical property of the compound. The methyl groups preserved the ligands on both side in the ring by making strong bond grid which lead the consistent chemical property. Since the methyl and carbonyl groups were found to be active, this is the main cause for the present compound to have rich analgesic and antipyretic properties.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Molecular Structure - Volume 1127, 5 January 2017, Pages 611-625
نویسندگان
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