کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1409694 1501829 2011 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A comparative study of dynamic NMR spectroscopy in analysis of selected N-alkyl-, N-acyl-, and halogenated cytisine derivatives
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آلی
پیش نمایش صفحه اول مقاله
A comparative study of dynamic NMR spectroscopy in analysis of selected N-alkyl-, N-acyl-, and halogenated cytisine derivatives
چکیده انگلیسی

New halogenated derivatives of (-)-cytisine were synthesized: 3-bromo-N-acetylcytisine, 5-bromo-N-acetylcytisine, 3,5-dibromo-N-acetylcytisine, 3-iodo-N-acetylcytisine, 5-iodo-N-acetylcytisine, 3,5-diiodo-N-acetylcytisine. Their structures were established on the basis of their NMR spectra and X-ray diffraction method. The crystal structures confirmed the chair conformation of ring C, while in solution all these compounds are in cis–trans conformational equilibrium with ring C in chair and boat conformation. Additionally, the correct X-ray structure of N-benzylcytisine was resolved.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Molecular Structure - Volume 985, Issues 2–3, 31 January 2011, Pages 157–166
نویسندگان
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