Study of the interaction between quinocetone and bovine serum albumin by spectroscopic approaches

► We explored the interaction of BSA and QCT by spectroscopic methods. ► The fluorescence quenching mechanism is combined quenching. ► Hydrogen bonds and van der Waals forces were the main force. ► The binding constants, binding sites and thermodynamic parameters were calculated. ► The QCT affects the conformation of tryptophan residues' microregion.