کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1427759 | 1509087 | 2006 | 18 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Gastroretentive dosage forms: Overview and special case of Helicobacter pylori
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی مواد
بیومتریال
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Gastroretentive dosage forms: Overview and special case of Helicobacter pylori Gastroretentive dosage forms: Overview and special case of Helicobacter pylori](/preview/png/1427759.png)
چکیده انگلیسی
The challenge to develop efficient gastroretentive dosage forms began about 20 years ago, following the discovery of Helicobacter pylori by Warren and Marshall. In order to understand the real difficulty of increasing the gastric residence time of a dosage form, we have first summarized the important physiologic parameters, which act upon the gastric residence time. Afterwards, we have reviewed the different drug delivery systems designed until now, i.e. high-density, intragastric floating, expandable, superporous hydrogel, mucoadhesive and magnetic systems. Finally, we have focused on gastroretentive dosage forms especially designed against H. pylori, including specific targeting systems against this bacterium.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Controlled Release - Volume 111, Issues 1–2, 10 March 2006, Pages 1–18
Journal: Journal of Controlled Release - Volume 111, Issues 1–2, 10 March 2006, Pages 1–18
نویسندگان
P.L. Bardonnet, V. Faivre, W.J. Pugh, J.C. Piffaretti, F. Falson,