کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
14553 1228 2011 18 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cyclosporin A — A review on fermentative production, downstream processing and pharmacological applications
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Cyclosporin A — A review on fermentative production, downstream processing and pharmacological applications
چکیده انگلیسی

In present times, the immunosuppressants have gained considerable importance in the world market. Cyclosporin A (CyA) is a cyclic undecapeptide with a variety of biological activities including immunosuppressive, anti-inflammatory, antifungal and antiparasitic properties. CyA is produced by various types of fermentation techniques using Tolypocladium inflatum. In the present review, we discuss the biosynthetic pathway, fermentative production, downstream processing and pharmacological activities of CyA.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biotechnology Advances - Volume 29, Issue 4, July–August 2011, Pages 418–435
نویسندگان
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