کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
14565 1230 2008 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
RNA interference: The story of gene silencing in plants and humans
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
RNA interference: The story of gene silencing in plants and humans
چکیده انگلیسی

RNA interference is an exciting field of functional genomics that can silence viral genes. This property of interfering RNA can be used to combat viral diseases of plants as well as animals and humans. It is a short sequence of nucleic acid that can bind to the mRNA of the gene and interferes the process of its expression. It is diverse in occurrence as well as in applications. It occurs from nematodes to fungi and can cause gene silencing in plants, animals and human beings. Small interfering RNAs are used to silence plant viral genes and in production of therapeutic drugs against Hepatitis or Immuno-deficiency viruses in human. In this review, we will discuss the history, mechanism and applications of RNA interference in plant, animal and human research.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biotechnology Advances - Volume 26, Issue 3, May–June 2008, Pages 202–209
نویسندگان
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