Preparation of 10 μm scale monodispersed particles by jetting flow in coaxial microfluidic devices

Ten microns scale monodispersed particles have a widespread use in various applications. In this work, we developed a novel and facile microfluidic method to generate various 10 μm scale monodispersed polymer and hydrogel particles. The method involves the formation of monodispersed droplets by using stable jetting flow in a simple coaxial microfluidic device and solidifying the droplets in situ. We also added functional additives such as fluorescent dye into monomer droplets to generate functional fluorescent particles. The microfluidic method presented here is versatile to various materials and can add functional additives to form functional microparticles.

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► A novel and facile microfluidic method to generate various 10 μm scale monodispersed particles was developed.
► Functional additives such as fluorescent dye were added into monomer droplets to generate functional fluorescent particles.
► The microfluidic method is versatile to various materials to generate polymer and hydrogel particles.