Electrocatalytic activity of Pt doped TiO2 nanotubes catalysts for glucose determination

A hybrid system of titanium dioxide nanotubes (TNTs) incorporated with poly(amidoamine) dendrimers-encapsulated platinum nanoparticles (Pt-DENs) was constructed in a neutral aqueous solution through electrostatic interaction. The TNTs/Pt-DENs nanohybrids immobilized glucose oxidase (GOx) was used to modify a glassy carbon electrode (GCE) for detecting the electrocatalytic response to the reduction of glucose. The structures of nanohybrids were characterized by TEM, XRD and FT-IR, the performance of modified electrodes was characterized by cyclic voltammetry (CV) and amerometric measurements, respectively. The modified electrodes, which had a fast response of glucose oxidase less than 3 s, could be used for the determination of glucose oxidase ranging from 2 μM to 12 mM. The detection limits were 1 μM at signal-to-noise ratio of 3.