Fe3O4@Pt nanoparticles with enhanced peroxidase-like catalytic activity

• Platinum modified Fe3O4 nanoparticles were prepared by a simple method.
• The activity of Fe3O4@Pt NPs as peroxidase mimetics was evaluated in the TMB–H2O2 system.
• Fe3O4@Pt NPs exhibited a larger Kcat value than that of Fe3O4 NPs, suggesting a higher peroxidase-like activity.

Pt modified Fe3O4 magnetic nanoparticles (Fe3O4@Pt NPs) were synthesized by a simple method. The morphology and crystal structure of the as-prepared nanocomposite were characterized by TEM, XRD and EDS. The peroxidase-like catalytic activity of the synthesized nanoparticles was also investigated. Catalysis was found to follow Michaelis–Menten kinetics. The calculated kinetic parameters of the Fe3O4@Pt NPs show that they exhibited strong affinity with substrates and enhanced catalytic activity than that of Fe3O4 nanoparticles, suggesting a higher peroxidase-like activity.