کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1696212 | 1519128 | 2008 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Itraconazole–Laponite: Kinetics and mechanism of drug release
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
علوم زمین و سیارات
ژئوشیمی و پترولوژی
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چکیده انگلیسی
A clay-drug nanohybrid was prepared by interfacial boundary ion exchange reaction, from which the release mechanism of a poorly water soluble drug, itraconazole, was studied systematically. The effect of cation types on drug release was investigated on the basis of a UPS 25 guide line and the effect of Laponite dissolution was also studied at pH = 1.2. To describe the release patterns, mathematical modeling was preformed using first-order, Elovich, parabolic diffusion, and power function equations.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Applied Clay Science - Volume 40, Issues 1–4, June 2008, Pages 99–107
Journal: Applied Clay Science - Volume 40, Issues 1–4, June 2008, Pages 99–107
نویسندگان
Hyun Jung, Hyun-Mi Kim, Young Bin Choy, Seong-Ju Hwang, Jin-Ho Choy,