کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1696212 1519128 2008 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Itraconazole–Laponite: Kinetics and mechanism of drug release
موضوعات مرتبط
مهندسی و علوم پایه علوم زمین و سیارات ژئوشیمی و پترولوژی
پیش نمایش صفحه اول مقاله
Itraconazole–Laponite: Kinetics and mechanism of drug release
چکیده انگلیسی

A clay-drug nanohybrid was prepared by interfacial boundary ion exchange reaction, from which the release mechanism of a poorly water soluble drug, itraconazole, was studied systematically. The effect of cation types on drug release was investigated on the basis of a UPS 25 guide line and the effect of Laponite dissolution was also studied at pH = 1.2. To describe the release patterns, mathematical modeling was preformed using first-order, Elovich, parabolic diffusion, and power function equations.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Applied Clay Science - Volume 40, Issues 1–4, June 2008, Pages 99–107
نویسندگان
, , , , ,