کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1704731 1012414 2011 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Modelling and optimization for a switched system in microbial fed-batch culture
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مکانیک محاسباتی
پیش نمایش صفحه اول مقاله
Modelling and optimization for a switched system in microbial fed-batch culture
چکیده انگلیسی

This paper considers modelling and optimization of a microbial fed-batch fermentation process. A switched system with variable switching instants is proposed to describe the fermentation process of glycerol bioconversion to 1,3-propanediol (1,3-PD). Taking the concentration of 1,3-PD at the terminal time as the cost function and the switching instants as optimization variables, an optimization model involving switched system and subject to continuous state inequality constraints is then presented. By introducing a time-scaling transform, the optimization model is transcribed into an equivalent one with parameters and fixed switching instants. A computational approach to seek the optimal solution is constructed on the basis of constraint transcription and smoothing approximation techniques. Numerical results show that, by employing the optimal switching instants, the concentration of 1,3-PD can be increased considerably compared with previous results.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Applied Mathematical Modelling - Volume 35, Issue 7, July 2011, Pages 3276–3284
نویسندگان
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