A techno-economic analysis of biodiesel biorefineries: Assessment of integrated designs for the co-production of fuels and chemicals

►We simulate alternative schemes for integrated biorefineries highlighting the co-production of fuels and chemicals through glycerol bioconversion to succinic acid. ► We perform single- and multi-objective optimization to compute optimal operating conditions that maximize biorefinery profitability and control CO2 emissions. ► We perform extensive economic analysis using measurements like Net Present Value and Internal Rate of Return robustly comparing biorefinery schemes.► We perform sensitivity analysis considering price fluctuations for raw materials, products/byproducts assessing profitability of biorefineries under different economic scenarios.