کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
1761448 | 1019648 | 2006 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Therapeutic ultrasound enhances medial collateral ligament repair in rats
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
مهندسی و علوم پایه
فیزیک و نجوم
آکوستیک و فرا صوت
پیش نمایش صفحه اول مقاله

چکیده انگلیسی
The purpose of this study was to evaluate the effects of therapeutic ultrasound (US) on medial collateral ligament healing. A total of 36 3-month-old male Sprague-Dawley rats with transected medial collateral ligaments were studied. Subjects were given 5-min pulsed US therapy (duty cycle; one application in 4 ms; 1:4) daily with different durations (1 day, 5 days and 10 days) and intensities (0, 0.5 and 2.3 W/cm2). After each treatment, the level of transforming growth factor beta-1 (TGF-β1) of the ligament was measured. TGF-β1 was not detected in the 1-day group. In the 5-day and 10-day groups, the levels of TGF-β1 were significantly up-regulated in the high-dose subgroup (p < 0.05). The 10-day group also registered a significantly higher expression of TGF-β1 than did the 5-day group (p < 0.05). The present findings suggest that pulsed US therapy may enhance ligament repair by up-regulating the extent of TGF-β1 in a high-dose application. Long-term treatment with this therapy could obtain further improvement. (E-mail: rsmcpleung@polyu.edu.hk)
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasound in Medicine & Biology - Volume 32, Issue 3, March 2006, Pages 449-452
Journal: Ultrasound in Medicine & Biology - Volume 32, Issue 3, March 2006, Pages 449-452
نویسندگان
Mason C.P. Leung, Gabriel Y.F. Ng, K.K. Yip,