کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
1761448 1019648 2006 4 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Therapeutic ultrasound enhances medial collateral ligament repair in rats
موضوعات مرتبط
مهندسی و علوم پایه فیزیک و نجوم آکوستیک و فرا صوت
پیش نمایش صفحه اول مقاله
Therapeutic ultrasound enhances medial collateral ligament repair in rats
چکیده انگلیسی
The purpose of this study was to evaluate the effects of therapeutic ultrasound (US) on medial collateral ligament healing. A total of 36 3-month-old male Sprague-Dawley rats with transected medial collateral ligaments were studied. Subjects were given 5-min pulsed US therapy (duty cycle; one application in 4 ms; 1:4) daily with different durations (1 day, 5 days and 10 days) and intensities (0, 0.5 and 2.3 W/cm2). After each treatment, the level of transforming growth factor beta-1 (TGF-β1) of the ligament was measured. TGF-β1 was not detected in the 1-day group. In the 5-day and 10-day groups, the levels of TGF-β1 were significantly up-regulated in the high-dose subgroup (p < 0.05). The 10-day group also registered a significantly higher expression of TGF-β1 than did the 5-day group (p < 0.05). The present findings suggest that pulsed US therapy may enhance ligament repair by up-regulating the extent of TGF-β1 in a high-dose application. Long-term treatment with this therapy could obtain further improvement. (E-mail: rsmcpleung@polyu.edu.hk)
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Ultrasound in Medicine & Biology - Volume 32, Issue 3, March 2006, Pages 449-452
نویسندگان
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